POST. MIKROBIOL.,
2007, 46, 4, 343-353
http://www.pm.microbiology.pl

 

HEMOLIZYNY ESCHERICHIA COLI

Beata Magdalena Sobieszczańska

Akademia Medyczna, Katedra i Zakład Mikrobiologii ul. Chałubińskiego 4;
50-368 Wrocław, e-mail: mapasobie@provider.pl, tel. 071 7841278

Wpłynęło w lipcu 2006 r.

1. Wstęp. 2. Hemolizyny E. coli aktywnie wydzielane do środowiska - pozakomórkowe. 2.1. Hemolizyna HlyA. 2.2. Hemolizyna ClyA. 3. Hemolizyny E. coli związane z komórką bakteryjną. 3.1. Hemolizyna b. 3.2. Enterohemolizyna (Ehx) enterokrwotocznych szczepów E. coli (EHEC). 3.3. Enterohemolizyny Ehlyl i Ehly2. 3.4. Hemolizyny kontaktowe E. coli. 3.5. Hemolizyna t. 3.6. Aktywność hemolityczna enteropatogennych E. coli (EPEC). 4. Podsumowanie

Escherichia coli hemolysins

Abstract: The best known hemolysin a of Escherichia coli (HlyA) is the prototype for a family of cytotoxins that are produced by a wide variety of gram-negative pathogens. Hemolysin-producing E. coli strains are isolated from patients with extraintestinal infections such as urinary tract infections or septicemia. The role of HlyA as a virulence factor of diarrheagenic E. coli was less obvious until the cell-detaching E. coli (CDEC) group, which is HlyA-producing and is responsible for diarrhea among infants, has been described. Apart from of extracellular hemolysins, E. coli may produce many cell-associated hemolysins e.g. enterohemolysins, hemolysin b, hemolysin of enterohemorrhagic E. coli strains. The ability of E. coli bacilli to produce cell-bound hemolysins may indicate an important role of contact of bacteria with host cells during infection. However, the exact role of these cell-bound hemolysins in pathogenicity of E. coli remains to be determined.

1. Introduction. 2. E. coli hemolysins actively secreted into the environment - Extracellular. 2.1. HlyA hemolysin. 2.2. ClyA hemolysin. 3. Hemolysins of E. coli associated with bacterial cell. 3.1. Hemolysin b. 3.2. Enterohemolysin (Ehx) of enterohemorrhagic E. coli strains (EHEC). 3.3. Enterohemolysins Ehlyl and Ehly2. 3.4. Contact hemolysins of E. coli. 3.5. Hemolysin t. 3.6. Hemolytic activity of enteropathogenic E. coli (EPEC). 4. Summary

Słowa kluczowe: enterohemolizyny, Escherichia coli, hemolizyny
Key words: enterohemolysins, Escherichia coli, hemolysins
 

 


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