POST. MIKROBIOL.,
2006, 45, 1, 27-38
http://www.pm.microbiology.pl

 

PEPTYDOGLIKAN GRAM-UJEMNYCH
PAŁECZKOWATYCH BAKTERII

Magdalena Karaś, Wincenty Drożański, Ryszard Russa
Zakład Mikrobiologii Ogólnej, Instytut Mikrobiologii i Biotechnologii, Uniwersytet Marii Curie-Skłodowskiej w Lublinie, ul Akademicka 19, 20-033 Lublin,
e-mai: russa@biotop.umcs.lublin.pl

Wpłynęło w maju 2005

1. Budowa chemiczna peptydoglikanu 2. Właściwości fizyczne mureiny bakterii Gram-ujemnych. 3. Modele architektury peptydoglikanu 3.1. Modele warstwowej mureiny. 3.2. Model trójwymiarowej mureiny w postaci rusztowania. 4. Wzrost woreczka mureinowego u bakterii Gram-ujemnych. 4.1. Synteza peptydoglikanu w modelu pasmowej mureiny. 4.2. Wzrost peptydoglikanu w modelu mureiny w postaci rusztowania. 5. Topografia wstawek nowo syntetyzowanego peptydoglikanu. 6. Podsumowanie

Peptidoglycan rod shape Gram-negative bacteria

Abstract: The murein sacculus is the essential part of cell wall of almost all eubacteria. It is needed to withstand the cytoplasmic turgor pressure and maintain a specific cell shape. The sacculus of bacteria appears to be a single molecule covering the inner membrane of bacteria. During bacteria growth the sacculus is enlarged continuously without rapture despite of its very thin structure in Gram-negative cells. In this review some known data about physical properties of murein and two concepts of its three dimensional structure are presented. One of them assumes that murein glycans are arranged parallel to the membrane and another one try to prove they extend perpendicular to it. They were shown advantages and disadvantage of both types of models. Recent studies with usage of GFP (green fluorescence protein) have let visualized the presence and role of helical bacterial cytoskeleton. Opinions of some authors about correlation between these actin-like structures and diftused murein synthesis in cylindrical part of sacculus are also presented in this article.

1. Chemical composition of peptidoglycan. 2. Physical properties of murein in Gram-negative bacteria. 3. Models of peptidoglycan architecture. 3.1. Models of layer murein. 3.2. Three dimensional scaffold model of murein. 4. Growth of murein sacculus of Gram-negative bacteria. 4.1. Peptidoglycan synthesis for model of layer murein. 4.2. Growth of peptidoglycan in scaffold model. 5. Topography intercalation of newly synthesized peptidoglycan. 6. Summary

Słowa kluczowe: bakterie Gram-ujemne, Mbl, modele mureiny, MreB,
                          peptydoglikan
Key words: Gram-negative bacteria, Mbl, models of murein, MreB, peptidoglycan

 


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