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BAKTERIOCYNY PALECZEK Z RODZAJU
PSEUDOMONAS
Katarzyna Gabriela Jachna-Sawicka, Eugenia Gospodarek
Roman Marian Bugalski
Katedra i Zakład Mikrobiologii AM, ul. M. Skłodowskiej-Curie 9, 85-094 Bydgoszcz
Wpłynęło w lutym 2004
1. Wprowadzenie. 2. Bakteriocyny pałeczek
Pseudomonas aeruginosa. 2.1. Piocyny R. 2.2. Piocyny F. 2.3. Związek między piocynami R i F, a bakteriofagami. 2.4. Piocyny S. 2.5. Genetyczna regulacja wytwarzania
piocyn. 3. Bakteriocyny pałeczek Pseudomonas sp., innych gatunków niż
P. aeruginosa, izolowanych ze środowiska naturalnego. 4. Zastosowanie bakteriocyn pałeczek
Pseudomonas sp. 5. Podsumowanie
Bacteriocins of
Pseudomonas sp.
Abstract: Strains of many bacterial species produce proteinaceous antimicrobial substances called bacteriocins. They are generally effective only against the same or closely related
species. The goal of this review is to describe what is known about bacteriocins of
Pseudomonas genus. Pseudomonas aeruginosa can produce three types of bacteriocins: R-, F- and S-type pyocins. R- and F-type pyocins resemble tails of bacteriophages. They are protease- and nuclease-resistant. The comparison of pyocins and bacteriophages genes let to conclude that R-type pyocin is related to P2 phage, and F-type pyocin derive from A phage. S-type pyocins are soluble, colicin-like, protease-sensitive proteins. They are constituted of two components. The large component carries the killing activity and the small component is immunity protein. Pyocin genes are located on the chromosome of
P. aeruginosa. The production of pyocin is inducible by DNA-damaging agents e.g. ultraviolet irradiation. Many bacteriocins of
Pseudomonas sp. isolated from the environment were purified and characterized. They have variety physical and chemical properties and spectrum of activity. It's consider to use some pyocins of P. aeruginosa as alternative to clasical antibiotics almost against multidrug-resistance strains. Some bacteriocins of
Pseudomonas sp. may be used as biological control agents in plant
diseases.
1. Introduction. 2. The bacteriocins of
Pseudomonas aeruginosa. 2.1. R-type pyocins. 2.2. F-type
pyocins. 2.3. Relationship between R-type and F-type pyocin, and
bacteriophages. 2.4. S-type pyocins. 2.5. Genetic regulation of pyocin
syntesis. 3. Bacteriocins of Pseudomonas sp., other than
Pseudomonas aeruginosa species, isolated from the
environment. 4. Applications of bacteriocin of Pseudomonas sp. 5. Summary
Słowa kluczowe: bakteriocyny, piocyny,
Pseudomonas
Key words: bacteriocins, pyocins, Pseudomonas |
