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Significance of Corynebacterium
spp. in hospital infections
Abstract: Corynebacterium
species are
widely distributed in the environment and are prominent members of
the normal skin and mucous membrane flora. These organisms are
often regarded as contaminants, with little or no capacity to
cause human infections. Recent evidence suggests that the
nondiphtherial corynebacteria
cause a spectrum of clinical illnesses including skin, urinary
tract infections, and endocarditis, sepsis, pneumonia,
osteomyelitis, endophtalmitis.
More and more
often multiple resistante species are isolated, mostly C. urealyticum,
C. jeikeium and C. amycolatum.
Corynebacterium infections occurred mainly in patients
hospitalized for a long period who are severly immunocompromised
and elderly.
A certain percentage of corynebacteria
isolated from clinical specimens still represents undescribed
taxa, and make problem with identification and susceptibility
testing.
However, the predominant of corynebacteria
in material from normally sterile sites should be considered
as a possible cause of disease.
This review presents the species characteristic, which can
have meaning in human infections.
1. Infections
epidemiology of Corynebacterium
spp. 2. Clinical significance of opportunistic Corynebacterium spp. 2.1. Lipophilic Corynebacterium spp. 2.1.1. Corynebacterium jeikeium 2.1.2. Corynebacterium urealyticum 2.1.3. Comynebacterium lipophiloflavum 2.2. Nonlipophilic Corynebacterium
spp. 2.2.1. Comynebacterium
xerosis 2.2.2. Corynebacterium
minutissimum 2.2.3. Corynebacterium
striatum 2.2.4. Corynebacterium
amycolatum 2.2.5. Corynebacterium
pseudodiphtheriticum 2.2.6. Corynebacterium
afermentans, Corynebacterium propinquum 3. Conclusions |
